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21c Museum Hotel St Louis

8.8/101421 reviewsSaint Louis

Luxurious Accommodation Experience the elegance and comfort of 21c Museum Hotel St Louis, offering 4-star rooms with modern amenities including air conditioning, flat-screen TVs, and plush bedding. Art and Culture Immerse yourself in art at our hotel, featuring a contemporary art museum within the premises, showcasing thought-provoking exhibitions and installations. Relaxation and Dining Unwind by taking a dip in the indoor pool or savor a delicious meal at the on-site restaurant. Enjoy a convenient stay with room service and a 24-hour front desk at your disposal. Book your stay at 21c Museum Hotel St Louis for a perfect blend of luxury and artistry.

What this place offers

  • Fitness facilities
  • WiFi available
  • Free WiFi
  • Parking
  • Non-smoking rooms
  • Air conditioning

Policies & house rules

  • Check-in from 16:00
  • Check-out until 11:00
  • Children welcome
  • Pets allowed
  • Paid parking

Guests are required to show a photo ID and credit card upon check-in. Please note that all Special Requests are subject to availability and additional charges may apply. A deposit may be required at the property.

Available rooms

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1421 reviews

Guests liked

  • Friendly staff
  • Unique amenities
  • Comfortable rooms

Guests mentioned

  • Cleanliness issues
  • Management service shortcomings
  • Parking difficulties

  • nautica

    US · extended_group · Oct 2026

    10/10

  • Alesa

    US · family_with_children · Oct 2026

    10/10

    Relaxing atmosphere

    Pay 55 for parking each night

  • Samiyyah

    US · solo_traveller · Oct 2026

    10/10

    I really enjoyed my stay! It was beautiful! The museum just added an extra layer to the stay!

    I loved the aesthetic of the hotel

    I didn’t like that my sheets had small stains and hair! If you’re going to charge people 5 star prices! Housekeeping should do 5 star cleaning in rooms! Especially if guest are bring their pets!

  • Michael

    GB · couple · Sep 2026

    10/10

  • JOHN

    US · couple · Sep 2026

    10/10

    peaceful & enriching

Location

1528 Locust street · Saint Louis

What's nearby

  • Citygarden (downtown sculpture park)Park · 0.6 km
  • Busch Stadium (St. Louis Cardinals)Entertainment · 0.7 km
  • St. Louis Union Station & St. Louis AquariumEntertainment · 0.8 km
  • St. Louis Gateway Transportation Center (Amtrak / bus)Train station · 0.9 km
  • Gateway Arch (Gateway Arch National Park)Landmark · 1 km
  • Old CourthouseLandmark · 1 km
  • City MuseumMuseum · 2 km
  • Forest ParkPark · 7 km
  • Saint Louis Art MuseumMuseum · 7 km
  • St. Louis Lambert International Airport (STL)Airport · 16 km